By Evgeni N. Timin, Stanislav Berjukow, Steffen Hering (auth.), Stefan I. McDonough (eds.)
Voltage-gated calcium channels are serious regulators of cytoplasmic degrees of calcium, the common signaling ion. As such, calcium channels set off a variety of mobile features, from muscle contraction to neurotransmitter secretion, and are vital avid gamers in human disorder. well known within the frightened, cardiovascular, and endocrine structures, individuals of the calcium channel relatives are goals for latest antihypertensive and anticonvulsant medications. furthermore, they're rising ambitions for medicines to regard an awfully assorted team of issues, together with ache, cerebral ischemia, cardiac arrhythmia, and migraine. This e-book studies the compounds that focus on person calcium channel subtypes and the mobile and behavioral features ruled by way of every one diversified channel. It includes details for uncomplicated scientists utilizing calcium channel antagonists as experimental instruments, for behavioralists learning animal versions of human sickness, and for pharmaceutical scientists attracted to growing the subsequent new release of calcium channel-targeted medications. a number of elements make a complete ebook on calcium channel pharmacology timely.
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