By Tse-Chao Hua, Bao-Lin Liu, Haimei Zhang
Freeze-drying is a crucial upkeep procedure for heat-sensitive prescribed drugs and meals. items are first frozen, then dried in a vacuum at low temperature through sublimation and desorption, instead of by means of the applying of warmth. The ensuing goods could be saved at room temperature for lengthy classes. This informative textual content addresses either ideas and perform during this area.
The first bankruptcy introduces freeze-drying. The authors then evaluate the basics of the approach, heat-mass move analyses, modelling of the drying method and the gear hired. extra chapters specialize in freeze-drying of nutrients, freeze-drying of prescribed drugs and the protecting brokers and ingredients utilized. the ultimate bankruptcy covers the $64000 matters of disinfection, sterilization and technique validation.
Freeze-drying of pharmaceutical and nutrients items is a vital reference for foodstuff, pharmaceutical and refrigeration engineers and scientists with an curiosity in protection suggestions. it is going to even be of use to scholars in those fields.
- Addresses the foundations and practices utilized in this significant upkeep technique
- Explains the basics of heat-mass move research, modelling and the apparatus used
- Discusses the significance of disinfection, sterilization and procedure validation
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